Introduction:
Fragile X is a family of genetic conditions, which can impact individuals and families in various ways. These genetic conditions are related in that they are all caused by gene changes in the same gene, called the FMR1 gene.

Fragile X Includes:
As they grow up, children also experience a variety of challenges and transitions. Some are predictable and part of the life of every child; some are less usual. Children face transitions such as entering school, taking new subjects, changing classrooms and teachers, making new friends, trying new activities and moving to new homes or cities. They might also include certain losses, like losing a favorite possession, a pet or a friend. The illness or death of a family member or loss of a parent through divorce is especially traumatic. These times can be painful for school-age children, and parents need to provide support and attention.

Fragile X Syndrome (FXS), the most common cause of inherited mental impairment. This impairment can range from learning disabilities to more severe cognitive or intellectual disabilities. (Sometimes referred to as mental retardation.) FXS is the most common known cause of autism or "autistic-like" behaviors. Symptoms also can include characteristic physical and behavioral features and delays in speech and language development.

Fragile X-associated tremor/ataxia syndrome (FXTAS), a condition which affects balance, tremor and memory in some older male gene carriers.

Fragile X-associated primary ovarian insufficiency (FXPOI), a problem with ovarian function which can lead to infertility and early menopause in some female gene carriers.

Some gene carriers do not exhibit any of these features.

Fragile X can be passed on in a family by individuals who have no apparent signs of this genetic condition. In some families a number of family members appear to be affected, whereas in other families a newly diagnosed individual may be the first family member to exhibit symptoms.